Brain Exposome · 腦健康 Exposome 檢測

An educational, front-end-only brain-health self-check and interactive world map, grounded in the 2024 Lancet Commission on dementia's 14 modifiable risk factors plus cumulative air-pollution (PM2.5) exposure. It estimates an educational "brain-age acceleration" reference value and visualises, country by country, dementia prevalence, PM2.5, population aging, PAF (population attributable fraction) of modifiable risk, and MCI / SCD (mild cognitive impairment & subjective cognitive decline) prevalence.

All calculation happens in the browser — no personal data is uploaded or stored.

Deployed at https://brain-exposome.mattye.dev. Previously lived at mattye.dev/projects/dementia-exposome/; that path 301-redirects here.

Tech stack

• Astro 6 (static output) · plain CSS · no JS framework
• Leaflet for admin-1 (county/province) choropleth maps
• d3-geo orthographic canvas globe for the national world layer
• Data pipeline in Python (scripts/build_data.py)

Develop

npm install
npm run dev        # http://localhost:4321
npm run build      # → dist/
npm run preview

Data

Derived, ready-to-serve assets live in public/data/ (committed). Raw, non-redistributable inputs (NCD-RisC / WHO GHO / GBD / WorldPop / publisher PDFs) live in scripts/_data_in/ (gitignored). Regenerate the derived assets with:

python scripts/build_data.py

Sources, PAF math, and per-country provenance are documented in docs/dementia-exposome/ and cited in-app (references §). Key backbone sources: Livingston et al. 2024 (Lancet Commission), NCD-RisC, WHO Global Health Observatory, GBD 2021, World Bank, and Bai et al. 2022 (global MCI meta-analysis).

Layout

public/data/        derived, served data (dementia, exposome, pm25, aging, mci, scd, geo)
scripts/            build_data.py + helpers
src/pages/index.astro   the single-page app
src/layouts/ src/components/ src/styles/
docs/dementia-exposome/ methodology, provenance, data-refresh + migration notes

All estimates are modelled and for education only — not clinical or diagnostic advice.