Mirobody
The canonical registry of human health — roughly two thousand standardized indicators, clinical and lifestyle, resolved into one language.
A decentralized framework for drug assessment for ranking treatments by real-world effectiveness and outcome labels showing the positive and negative effects of every food and drug in the world.
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A platonic ideal of fda.gov to 80X the pace of clinical discovery! 🚀
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Read the full README ↗dFDA (Decentralized Framework for Drug Assessment) is open-source software for ranking treatments by real-world outcomes and publishing an Outcome Label for each one. It is designed so patient records stay with patients and clinics and only aggregate results are shared; that sharing isn't built yet (see What works today below). It is an independent open-source project, not affiliated with, endorsed by, or acting on behalf of the U.S. Food and Drug Administration.
flowchart LR
SAFE["Digital Twin Safe<br/>(patient's own data)"] -- "OAuth: share with my doctor" --> NODE["Clinic Node<br/>(runs at the clinic)"]
NODE -- "Summary File<br/>(aggregates only)" --> AGG["Global Aggregator"]
AGG --> SITE["dfda.earth<br/>Treatment Rankings + Outcome Labels"]
What works today
| Piece | Status | Where |
|---|---|---|
| Web app | Prototype: patient condition and treatment tracking, 0–10 treatment ratings, outcome-label schema. Runs as dfda.earth or as a clinic's Clinic Node. No federation yet. | apps/web |
| N-of-1 causal analysis engine | Working TypeScript library | optimitron/packages/optimizer |
| Patient ratings | Live for 162 conditions and ~3,900 treatments, reported by patients | crowdsourcingcures.org/conditions |
| Automated N-of-1 studies | ~15,800 legacy observational analyses, not peer reviewed | studies.crowdsourcingcures.org |
| Summary File spec, Codebook, Global Aggregator | Designed, not built yet | — |
See Apps and features for the current application, planned packages, and features to extract from related repositories. The implementation sequence and data rules are in docs/MIGRATION.md, the authoritative implementation roadmap. The broader vision below is background, not a second backlog or a claim that every feature exists.
Billions of people are suffering needlessly because the current system of clinical research, diagnosis, and treatment sucks because:
The Cure Acceleration Act creates:
👉 Read the Full Cure Acceleration Act
The current system of clinical research, diagnosis, and treatment is failing the billions of people are suffering from chronic diseases.
👉 Problems we're trying to fix...
By harnessing global collective intelligence and oceans of real-world data, we hope to emulate Wikipedia's speed of knowledge generation.
So in the 90's, Microsoft spent billions hiring thousands of PhDs to create Encarta, the greatest encyclopedia in history. A decade later, when Wikipedia was created, the general consensus was that it was going to be a dumpster fire of lies. Surprisingly, Wikipedia ended up generating information 50X faster than Encarta and was about 1000X cheaper without any loss in accuracy. This is the magical power of crowdsourcing and open collaboration.
Our crazy theory is that we can accomplish the same great feat in the realm of clinical research. By crowdsourcing real-world data and observations from patients, clinicians, and researchers, we hope to generate clinical discoveries 50X faster and 1000X cheaper than current systems.
This is a very high-level overview of the architecture. The three primary primitive components of the framework are:
This is the beginning of the README. Read the rest at the original. Read the full README ↗